Inactive Ingredient: Wax.
"HeadOn claims to relieve headaches through homeopathic means -- by administering minute doses of agents said to cause the pain. Miralus Healthcare, the Plantation, Fla.-based company that makes the product, said it has sold more than 5 million tubes of the stuff, at around $8 a pop, in the past 11 months.[...]
HeadOn, [the company vice president] said, contains highly dilute amounts of white bryony (a type of vine) and potassium dichromate -- said by the Pharmacopoeia to cause headaches. Mainstream doctors don't believe these substances cause or cure headaches, said Seymour Diamond, director of the Diamond Headache Clinic in Chicago and the inpatient headache unit at St. Joseph Hospital. Diamond said any relief reported by HeadOn users is likely due to the placebo effect, which occurs 30 to 40 percent of the time with headache remedies. "I see nothing in this product that has any validity whatsoever," Diamond said."
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[via WP via wikipedia via SA]